Curcumin is the most active curcuminoids in turmeric, followed by demethoxycurcumin and bisdemethoxycurcumin. Turmeric has been used by humans for more than 4,000 years. It belongs to the ginger family. It is the source of the yellow color in curry. Turmeric was used in ancient India and Chinese medicine to treat inflammatory diseases, protect the liver, skin diseases and wounds. It can be called an herb aspirin.
Efficacy and role
Curcumin is a powerful antioxidant that protects the body from free radical damage. Its antioxidant capacity is proven to be comparable to vitamin E and vitamin C.
An in vitro study using bovine aortic endothelial cells to measure the effects of curcumin on stress oxidation showed that curcumin enhanced cellular resistance to oxidative damage over time.
Laboratory studies have shown that curcumin can exhibit anti-inflammatory effects by inhibiting pro-inflammatory factors, and exert anti-inflammatory effects by reducing histamine levels and increasing adrenaline secretion of anti-inflammatory substances. The laboratory has identified several Substances that can cause inflammation that can be inhibited by curcumin include phospholipase, lipoxygenase, cyclooxygenase 2, leukotrienes, thromboxane, prostaglandins, nitric oxide, etc.
3. Protect the liver and gallbladder
Antioxidative properties and mechanistic pro-inflammatory factors of curcumin protect the liver from many compounds, such as carbon tetrachloride, acetaminophen, and aflatoxins, among others.
Sodium curcumin, a salt of curcumin, exerts choleretic effects by increasing biliary excretion of bile salts, cholesterol and bilirubin, and increasing bile solubility.
4. Cardiovascular protection
Abnormal aggregation of platelets can easily lead to the formation of blood clots. Curcumin has been shown to prevent abnormal aggregation of platelets by enhancing prostacyclin synthesis and inhibiting thromboxane synthesis, thereby improving blood circulation.
At the same time, curcumin may reduce cholesterol and triglyceride levels in the body by reducing the absorption of cholesterol in the intestines and increasing the conversion of cholesterol into bile acids in the liver. These effects can accelerate blood patency in the cardiovascular system to protect Cardiovascular health.
5. Antibacterial properties
Curcumin inhibits the reproduction of a variety of bacteria and fungal growth, and has moderate activity against some parasites and other protozoa. In an experiment in guinea pigs infected with dermatophytes and fungi, the disappearance of lesions was observed after 7 days of treatment with curcumin.
6. Relieves and treats stomach ulcers
Curcumin has been proven to relieve or treat gastric ulcers, and a clinical trial of 25 patients with gastric ulcers diagnosed by endoscopy showed that after taking 600 mg of turmeric powder five times a day for 4 weeks, 48% of the The ulcers healed completely, and 76% of the patients had no ulcers in their stomachs by endoscopy after 12 weeks.
At the same time, no obvious adverse reactions or abnormal blood index were reported in all subjects.
7. Maintain oral health
In folk remedies, a sore tooth is massaged with toasted turmeric powder to remove pain and swelling, or a paste of 1 teaspoon turmeric, ½ teaspoon salt, and ½ teaspoon mustard oil is rubbed against teeth and gums twice daily , relieves gingivitis and periodontitis.
A randomized trial found that gingival index and plaque index were recorded on days 0, 14, and 21 after continuous mouthwash with curcumin, and the results showed that curcumin played a role in the prevention of plaque and gingivitis. With a good effect.
In a number of studies involving cancer and cancer cells, it has been found that curcumin may play an inhibitory role in different aspects of various cancers. It effectively inhibits the uncontrolled metastases of melanoma cancer cells that cause skin cancer, also inhibits the proliferation of breast tumor cells, inhibits the activity of cancer-inducing chemicals in the skin, stomach, and colon, as well as by modulating protease activity to inhibit angiogenesis, thereby preventing the growth and metastasis of cancer cells.
At the same time, because of its own antioxidant properties,curcumin can scavenge free radicals and reduce the level of high glutathione caused by free radicals, thereby increasing liver detoxification and reducing the possibility of cell canceration.