Proanthocyanidins(OPC) are natural antioxidants which can scour free radicals. Grape seed, blueberry skin, lychee skin, dragon eyelid, mangosteen shell and so on contain this component, which belongs to biological flavonoid compounds in structure. Now experimental studies have found that procyanidins may have a variety of pharmacological effects.

1. Antioxidant effect

Proanthocyanidins have strong antioxidant properties, which can remove superoxide anion free radicals and hydroxyl free radicals. They have synergistic antioxidant properties with vitamin C, which can prevent collagen from free radical damage and properly protect skin from premature aging.

2. improve the vascular circulation system

By removing and preventing oxygen free radicals, improve the permeability and resistance of capillary, inhibit the injury of capillary wall, eliminate edema, improve capillary state, make blood flow into the brain, improve the state of brain hypoxia. Improve blood capillary bleeding in the eye, so that diabetic retinopathy can be improved.

3. Anti-inflammatory and allergic effect

Proanthocyanidins may inhibit coX-2 and thus inhibit the production of histamine, an inflammatory mediator, to play an anti-inflammatory role. Proanthocyanidins can prevent mast cells and basophils from being oxidized by anti-oxidation and keep the cells in a stable state without being sensitive to allergens or degranulating or producing allergenic mediators, thus playing an anti-allergic role.

4. Anti-tumor effect

Studies have shown that proanthocyanidins can inhibit and prevent various tumors, including cervical cancer, breast cancer, prostate cancer, skin cancer and colon cancer. Studies have shown that proanthocyanidins may induce apoptosis of tumor cells by activating apoptotic proteases in tumor cells or inhibit tumor proliferation by affecting tumor cell signal transduction.

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